Atypical network

From dermoscopedia

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 Editor: Ralph P. Braun

 Author(s): Katrin Kerl     ·  Ralph P. Braun
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Description This chapter covers histopathological correlation of atypical pigment networkNetwork with increased variability in the color, thickness, and spacing of the lines of the network; asymmetrically distributed; gray color in dermoscopyThe examination of [skin lesions] with a 'dermatoscope'. This traditionally consists of a magnifier (typically x10), a non-polarised light source, a transparent plate and a liquid medium between the instrument and the skin, and allows inspection of skin lesions unobstructed by skin surface reflections. Modern dermatoscopes dispense with the use of liquid medium and instead use polarised light to cancel out skin surface reflections.
Author(s) Katrin Kerl · Ralph P. Braun
Responsible author Ralph Braun→ send e-mail
Status released
Status update July 2, 2018
Status by Ralph P. Braun


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is irregularly meshed with lines that vary in width and degree of pigmentation and with “holes” that are heterogeneous in area and shape. An atypical networkNetwork with increased variability in the color, thickness, and spacing of the lines of the network; asymmetrically distributed; gray color shows foci with broader and darker pigmented linesstreaksThis glossary term has not yet been described.; the networkThis glossary term has not yet been described. often ends abruptly at the lesion’s periphery. An atypical network within a lesion may also appear perturbed and broken up, a finding referred to as “branched streaksBroadened or widened network with broken lines and incomplete connections”.

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On histolopathology, the irregular lines of an atypical network correspond to variation in the width, length, and spacing of the rete ridgesEpidermal extensions that project into the underlying dermis due to variation in the size, spacing, and tendency to confluence of nests of melanocytes. Rete ridgesEpidermal extensions that project into the underlying dermis that are elongated and widened by larger junctional nests of melanocytes would appear as darker and wider lines on dermoscopy. The atypical network is often seen in melanomaThis glossary term has not yet been described. and dysplastic neviThis glossary term has not yet been described..

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