Blink sign

From dermoscopedia

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 Authored by: Ralph P. Braun     ·  Ashfaq A. Marghoob

 Keywords:   polarized light · non polarized light · blink sign
Description In this chapter we describe the blink signWhile toggling between polarized and non polarized light, the structures that are more visibile with either one type of light will be enhanced and though blink at you in dermoscopyDermoscopy is a non invasive diagnostic method.
Author(s) Ralph P. Braun · Ashfaq A. Marghoob
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Status unknown
Status update June 12, 2017
Status by Ralph P. Braun


Certain dermoscopic structuresThis glossary term has not yet been described. are more conspicuous with nonpolarized dermoscopy (NPD), while others are more conspicuous with polarized dermoscopy (PD)[1] .
The introduction of hybrid dermoscopes now allow the user to toggle between polarized and nonpolarized light. We found that structures that are more conspicuous with either NPD or PD appear to “blink” when the observer toggles between light modes[2].
In our experience, the presence of crystalline structures, which can easily be confirmed via the blink sign, can assist in detecting amelanotic and nodular melanomaThis glossary term has not yet been described., thereby increasing diagnostic sensitivity. The presence of multiple milia cysts, which can also easily be seen via the blink testThis glossary term has not yet been described., increases diagnostic specificity by helping to correctly identify seborrheic keratosisThis glossary term has not yet been described..

ReferencesThis glossary term has not yet been described.
  1. Benvenuto-Andrade et al.: Differences between polarized light dermoscopy and immersion contact dermoscopy for the evaluation of skin lesions. Arch Dermatol 2007;143:329-38. PMID: 17372097. DOI.
  2. Braun et al.: The "blink sign" in dermoscopy. Arch Dermatol 2011;147:520. PMID: 21482914. DOI.