Factors influencing diagnostic accuracy
There is overwhelming evidence confirming, that dermoscopy improves the diagnostic accuracy for melanoma in comparison to inspection with unaided eye.
Type of algorithm used to evaluate the lesions
A number of diagnostic algorithms have been developed for the dermoscopic evaluation of pigmented lesions. Pattern analysis has been shown to have a higher specificity than the other algorithms, but no significant differences were found with regard to sensitivity.
- Pehamberger et al.: In vivo epiluminescence microscopy of pigmented skin lesions. I. Pattern analysis of pigmented skin lesions. J. Am. Acad. Dermatol. 1987;17:571-83. PMID: 3668002.
- Nachbar et al.: The ABCD rule of dermatoscopy. High prospective value in the diagnosis of doubtful melanocytic skin lesions. J. Am. Acad. Dermatol. 1994;30:551-9. PMID: 8157780.
- Argenziano et al.: Epiluminescence microscopy for the diagnosis of doubtful melanocytic skin lesions. Comparison of the ABCD rule of dermatoscopy and a new 7-point checklist based on pattern analysis. Arch Dermatol 1998;134:1563-70. PMID: 9875194.
- Menzies et al.: Frequency and morphologic characteristics of invasive melanomas lacking specific surface microscopic features. Arch Dermatol 1996;132:1178-82. PMID: 8859028.
- Kittler et al.: Diagnostic accuracy of dermoscopy. Lancet Oncol. 2002;3:159-65. PMID: 11902502.