Lacunae

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Description In this chapter we describe lacunae and its histopathological correlation
Author(s) Ralph P. Braun · Katrin Kerl
Responsible author Ralph Braun→ send e-mail
Status unknown
Status update May 27, 2017
Status by Ralph P. Braun


Lacunae are multiple well-demarcated round/oval and reddish structures arranged in clusters, separated by a white rim called septae. Histologically, they correspond to dilated, thin-walled vessels in the papillary dermis. Lacunae are the hallmark of vascular tumors, mainly angiomas. Dark (violaceous, blue-black, or black) lacunae reveal partially or completely thrombosed dermal vessels located deeper in the dermis, which are very specific of solitary angiokeratomas [1]. In targetoid hemosiderotic angiokeratomas a central dark lacunae is surrounded by a peripheral red-brownish homogeneous area. Histopathologically, it reveals the presence of less dilated angulated vascular spaces, hemosiderin deposition and extravasated erythrocytes in the mid and deep dermis [2]

Lacunae 27.jpg
Lacunae.jpg



References

  1. Zaballos et al.: Dermoscopy of solitary angiokeratomas: a morphological study. Arch Dermatol 2007;143:318-25. PMID: 17372096. DOI.
  2. Zaballos et al.: Dermoscopy of Targetoid Hemosiderotic Hemangioma: A Morphological Study of 35 Cases. Dermatology (Basel) 2015;231:339-44. PMID: 26458032. DOI.