Milky red globules / areas

From dermoscopedia

Main PageVascular structuresMilky red globules / areas
(1 vote)

 Editor: Ralph P. Braun

 Author(s): Ralph P. Braun
Description Describes dermoscopyThe examination of [skin lesions] with a 'dermatoscope'. This traditionally consists of a magnifier (typically x10), a non-polarised light source, a transparent plate and a liquid medium between the instrument and the skin, and allows inspection of skin lesions unobstructed by skin surface reflections. Modern dermatoscopes dispense with the use of liquid medium and instead use polarised light to cancel out skin surface reflections. of milky red globulesThis glossary term has not yet been described. / areas
Author(s) Ralph P. Braun
Responsible author Ralph Braun→ send e-mail
Status unknown
Status update June 29, 2017
Status by Ralph P. Braun


Milky red globulesThis glossary term has not yet been described.[1] are, as their name suggests, globules with a milky reddish coloring. These vascular structuresThis glossary term has not yet been described. may be observed within or near areas with a milky red color [2].

Milky red globules schematics.jpg

Differential diagnosisis the identification of the nature and cause of a certain phenomenon. Diagnosis is used in many different disciplines with variations in the use of logic, analytics, and experience to determine "cause and effect". In systems engineering and computer science, it is typically used to determine the causes of symptoms, mitigations, and solutions
Although milky red globules are not seen frequently, when present, they are highly suggestive of invasive melanomaThis glossary term has not yet been described. [3]. They may be valuable in the recognition of thicker amelanotic/hypomelanotic melanomaThis glossary term has not yet been described. (AHMamelanotic/hypomelanotic melanoma), which often do not have many noticeable or identifying features. In AHM, milky red globules/red areas were reported in 31% of thin melanomas (1mm) and in 93.3% of thick melanomas (1mm), as compared with 17.3% and 9.1% of amelanotic /hypomelanotic benign melanocyticThis glossary term has not yet been described. lesions and amelanotic/hypomelanotic non-melanocytic lesions, respectively. In another study, 4.7% of melanomas with vascular structures on dermoscopy contained milky red globules/areas, correlating with a PPV of 77.8%; only 0.5% of nonmelanoma lesions had these structuresThis glossary term has not yet been described.. Vascular blush, also known as erythematous blush, pink veil, or milky red areasMilky-white appearance or pinkish structureless areas ("strawberry and ice cream"-like), consisting a red vascular blush with no specific distinguishable vessels, represents a red or pink region that corresponds to an area with increased vascularity. Thus, vascular blush can be seen in lesions, such as dermatofibromas, vascular tumors, such as pyogenic granulomas, inflammatory lesions, and both melanoma and nonmelanoma skin cancers. Although vascular blush can be seen in neviThis glossary term has not yet been described., it tends to be more common and conspicuous in melanoma.

ReferencesThis is material contained in a footnote or bibliography holding further information.:
  1. An Atlas of Dermoscopy, Second Edition. Marghoob A. et al. CRC Press; 2012.
  2. Argenziano et al.: Vascular structures in skin tumors: a dermoscopy study. Arch Dermatol 2004;140:1485-9. PMID: 15611426. DOI.
  3. Braun et al.: Dermoscopy: what's new?. Clin. Dermatol. 2009;27:26-34. PMID: 19095151. DOI.