Sensitivity and Specificity

From dermoscopedia

Main PageDiagnostic accuracySensitivity and Specificity
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The majority of studies which have evaluated the diagnostic accuracyThis glossary term has not yet been described. of dermoscopyThe examination of [skin lesions] with a 'dermatoscope'. This traditionally consists of a magnifier (typically x10), a non-polarised light source, a transparent plate and a liquid medium between the instrument and the skin, and allows inspection of skin lesions unobstructed by skin surface reflections. Modern dermatoscopes dispense with the use of liquid medium and instead use polarised light to cancel out skin surface reflections. have relied on calculation of specificityThis glossary term has not yet been described. and sensitivityThis glossary term has not yet been described., by comparing the diagnosisis the identification of the nature and cause of a certain phenomenon. Diagnosis is used in many different disciplines with variations in the use of logic, analytics, and experience to determine "cause and effect". In systems engineering and computer science, it is typically used to determine the causes of symptoms, mitigations, and solutions made by dermoscopy with the histopathological diagnosis.

  • SpecificityThis glossary term has not yet been described.: the proportion of benignis any condition that is harmless in the long run pigmented skin lesions that are correctly identified by dermoscopy
  • SensitivityThis glossary term has not yet been described.: the proportion of melanomas that are correctly identified by dermoscopy

Advantages and Disadvantages

Advanages
  • Valid indicators of diagnostic testThis glossary term has not yet been described. performance
  • Easily understood
Disadvanages

The diagnosis made by dermoscopy has to be divided into two groups: benign and malignantThis glossary term has not yet been described.. This is surely an oversimplification of the diagnostic procedure of dermoscopy.

DermoscopyThe examination of [skin lesions] with a 'dermatoscope'. This traditionally consists of a magnifier (typically x10), a non-polarised light source, a transparent plate and a liquid medium between the instrument and the skin, and allows inspection of skin lesions unobstructed by skin surface reflections. Modern dermatoscopes dispense with the use of liquid medium and instead use polarised light to cancel out skin surface reflections. is a tool to minimize uncertainty, thus aiming to the correct interpretation of a dermoscopic finding and leading to a decision of the necessity of further diagnostic procedures (excision). However, the interpretation of the dermoscopic findings is also influenced by other variables:

  • Clinical impression of the lesion
  • Ageprocess of becoming older of the patient
  • Anatomic side
  • Number and appearance of other lesions on the same patient

Other disadvantages to the evaluation of diagnostic tests by their sensitivity and specificity include the prevalence of the disease of interest (in this case melanomaThis glossary term has not yet been described.) not being taken into account, and the difficulties of comparing two diagnostic tests.