Correlation of dermoscopic structures on mucosal sites

From dermoscopedia

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 Editor: Oriol Yélamos

 Author(s): Oriol Yélamos     ·  Ralph P. Braun
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Description This chapter describes histopathological correlation of dermoscopyThe examination of [skin lesions] with a 'dermatoscope'. This traditionally consists of a magnifier (typically x10), a non-polarised light source, a transparent plate and a liquid medium between the instrument and the skin, and allows inspection of skin lesions unobstructed by skin surface reflections. Modern dermatoscopes dispense with the use of liquid medium and instead use polarised light to cancel out skin surface reflections. structuresThis glossary term has not yet been described. on mucosal sites
Author(s) Oriol Yélamos · Ralph P. Braun
Responsible author Oriol Yélamos→ send e-mail
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Status update January 1, 2019
Status by Ralph P. Braun


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Studies about correlation between dermoscopy and histologyThis glossary term has not yet been described. of mucosal lesions are scarce. In addition, the histological diagnosisis the identification of the nature and cause of a certain phenomenon. Diagnosis is used in many different disciplines with variations in the use of logic, analytics, and experience to determine "cause and effect". In systems engineering and computer science, it is typically used to determine the causes of symptoms, mitigations, and solutions of melanocyticThis glossary term has not yet been described. lesions in mucosal sites can be challenging since benign and malignant lesions can present with atypical findings (Yélamos et al., 2016). The pigment networkThis glossary term has not yet been described. is usually absent in mucosal lesions, due to the nearly complete absence of rete ridgesEpidermal extensions that project into the underlying dermis. However, with the exception of the pigment networkGrid-like pattern consisting of interconnecting pigmented lines surrounding hypopigmented holes., melanocytic lesions of the mucosaThis glossary term has not yet been described. can present with dermoscopic structuresThis glossary term has not yet been described. similar to those seen in non-mucosal locations such as linesstreaksThis glossary term has not yet been described., dotsDots are small, round structures of less than 0.1 mm in diameter that have a red color when corresponding to blood vessels; however, when due to melanin, their color ranges from black, brown, to blue-gray depending on the depth and concentration of the melanin in the skin (Tyndall effect)./globulesThis glossary term has not yet been described., circles and structureless areas.

Multiple patternsThis glossary term has not yet been described. can be observed in benign melanocytic lesions of mucosae.

The homogenous patternstructureless any color

is composed of structureless brown areas on dermoscopy. Histologically, it reveals flattened rete ridges along with acanthosis (Lin et al., 2009). 

The ring-like pattern

presents with pigmented circlesThis glossary term has not yet been described., and the fish scale-like pattern shows half circles. They both share the same histopathological correlations revealing hyperpigmented rete ridges with skip areas of pigmentation at the top of the dermal papillae (Ferrari et al., 2014; Lin et al., 2009).

The parallel pattern

is composed of brown, linear parallel streakslines radial (always at periphery) 	streaks 	Reed nevus melanoma recurrent nevus (Ferrari et al., 2014) and the hyphal pattern consists of lines resembling fungal hyphae. Histologically, they corresponds to hyperpigmentation at the tip of the obliquely elongated rete ridgeThis glossary term has not yet been described. (Lin et al., 2009). 

The dotted-globular patternThis glossary term has not yet been described.

presents with multiple dots/globules with similar sizes and shapes and corresponds to locally aggregated melanin in the upper dermis (Lin et al., 2009). 

A multicomponent patternThis glossary term has not yet been described.

consisting of blue, gray and white colorsThis glossary term has not yet been described., regression structuresThis glossary term has not yet been described., blue-whitish veil and structureless areas can be seen in mucosal melanomas (Blum et al., 2011; Lin et al., 2009). Histologically, the correlation is similar to that described in non-mucosal locations.