Correlation of infectious diseases
Molluscum contagiosum
White/yellow amorphous structures
White to yellow amorphous structures are polylobular whitish to yellowish structures surrounding a central pore. Linear or branched vessels ('red corona') are seen at the periphery (Vázquez-López et al., 2004). This is the typical dermoscopic pattern of molluscum contagiosum. Histologically, these white structures correspond to endophytic lobules of hyperplastic squamous epithelium expanding into the dermis, displacing dermal dilated vessels (Morales et al., 2005).
Warts
Multiple dark dots
Multiple dark dots are black/red dots within a well-defined yellowish area are characteristic of plantar warts. Recently, an histopathologic study of 18 palmoplantar warts found no thrombosed vessels, suggesting that the presence of dark dots is secondary to intracorneal hemorrhages and not to dermal microthrombi (Fried et al., 2018).
Scabies
Dark-brown triangular structures
A small brown triangular structure (“delta-wing jet sign”) located at the end of a subtle whitish curved line is highly specific of scabies (add specificity and reference). Histopathologically, the brown triangle corresponds to the pigmented anterior part of the parasite (figure). The whitish curved line reveals the burrow of the mite (Argenziano et al., 1997b).
