Correlation of seborrheic keratosis

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 Editor: Ralph P. Braun

 Author(s): Ralph P. Braun, Oriol Yélamos

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Description	This chapter covers the correlation of seborrheic keratosis
Author(s)	Oriol Yélamos · Ralph P. Braun
Responsible author	Ralph Braun → send e-mail
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Status update	January 1, 2019
Status by	Ralph P. Braun

Seborrheic keratoses, Seborrheic keratosis, Dermoscopy, Histopathology Correlation of seborrheic keratosis – cite! Correlation of seborrheic keratosis (message) Correlation of seborrheic keratosis – participate!

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Fissures and ridges

Fissures and ridges describe multiple thick lines that resemble the gyri (ridges) and sulci (fissures) of the brain (Kittler et al., 2016; Malvehy et al., 2006). Histopathologically, they correspond to epidermal clefts filled with keratin (Minagawa, 2017).

Milia-like cysts

Milia-like cysts are whitish or yellowish round structures. Under non-polarized dermoscopy these structures shine brightly (Braun et al., 2011). Histopathologically, they reveal intraepidermal keratin pseudocysts (Minagawa, 2017). Milia-like cysts are highly suggestive of SK, but can be observed in BCC and papillomatous melanocytic lesions, including melanoma (Carrera et al., 2017).

Comedo-like openings and crypts

Comedo-like openings are dark (brown/black) round to oval invaginations. Crypts are similar, but more elongated and larger (Kittler et al., 2016a). Histologically, they reveal epidermal invaginations filled with keratin (Minagawa, 2017). They are associated with SKs, although can be seen in any papillomatous lesion, such as intradermal nevi and melanoma (Carrera et al., 2017).