Differences between histologic and dermoscopic criteria

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Main PageHistopathologic correlation of dermoscopic structuresDifferences between histologic and dermoscopic criteria
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 Authored by: Ralph P. Braun     ·  Katrin Kerl

 Keywords:   pathology · dermatopathology · histology
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Description In this chapter we describe the difference between histologic and dermoscopyDermoscopy is a non invasive diagnostic method. criteriaThis glossary term has not yet been described.
Author(s) Ralph P. Braun · Katrin Kerl
Owner Ralph Braun→ send e-mail
Status released
Status update May 24, 2017
Status by Ralph P. Braun
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Histopathologic evaluation is performed on vertical sections of tissue, allowing the assessment of the full depth of the lesion from scanning magnification to a cellular-level magnification.

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HistopathologyThis glossary term has not yet been described. is performed on paraffin-embedded tissue, allowing for special stains and immunohistochemical techniques that may assist in diagnosisThis glossary term has not yet been described.. Dermoscopic evaluation is based on a horizontal view of the entire lesion.
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Another advantage of dermoscopy examination is that the clinican can examine the other lesions of the patient and that he or she can integrate the findings in the context of the patient.
Dermoscopic structures and colors are two-dimensional surface projections of tissue structures (e.g., melanocyticThis glossary term has not yet been described. nests and blood vesselsThis glossary term has not yet been described.). The dermoscopist sees the entire in the horizontal plane. The inspection of the skin by the dermoscopist is generally limited in depth to the papillary dermis. Another important limitation is that, dermoscopy does not allow the evaluation of the lesion at a cellular level.
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In addition the dermatopathologist has access to special stains which provide additional information (MelanA, S100, HMB45 etc.)

An important advantage is dermoscopy allows the follow up of lesions. This provides important information regarding the lesion’s biology and dynamic. With dermoscopy, we can identify “colors” and “structures” that are not perceived by the unaided eye.