Granularity / Peppering
|Description||This chapter describes histopathological correlation of the dermoscopyThe examination of [skin lesions] with a 'dermatoscope'. This traditionally consists of a magnifier (typically x10), a non-polarised light source, a transparent plate and a liquid medium between the instrument and the skin, and allows inspection of skin lesions unobstructed by skin surface reflections. Modern dermatoscopes dispense with the use of liquid medium and instead use polarised light to cancel out skin surface reflections. term granularityThis glossary term has not yet been described. or pepperingGray dots|
|Author(s)||Ralph P. Braun|
|Responsible author||Ralph Braun → send e-mail|
|Status update||July 2, 2018|
|Status by||Ralph P. Braun|
GranularityThis glossary term has not yet been described. (also known as “peppering”) is defined as accumulation of multiple very small (<0.1 mm), nondescript, blue-grey dotsDots are small, round structures of less than 0.1 mm in diameter that have a red color when corresponding to blood vessels; however, when due to melanin, their color ranges from black, brown, to blue-gray depending on the depth and concentration of the melanin in the skin (Tyndall effect).. If a large area shows dense, confluent granularity, it is difficultneeding much effort or skill to accomplish to distinguish from blue-white veil, however, clinically, granularity often is seen in macular portions of the lesion, while blue-white veil is seen in palpable areas. Histopathologically, granularity correlates with melanin in the superficialThis glossary term has not yet been described. dermis, either as fine melanin particles in melanophages or extracellular “dust-like” particles. When granularity is encountered in neviThis glossary term has not yet been described. it tends to encompass less than 10% of the lesion’s surface area. In contrast, in melanomaThis glossary term has not yet been described. the granularity often encompasses more than 50% of the lesion’s surface area.