Regression structures / Blue white structures
|Description||In this chapter we describe blue white structuresterm used for flat areas with white (scarlike) and blue color. This has to be distinguisehd from blue white veil. networkThis glossary term has not yet been described. and its histopathological correlation|
|Author(s)||Ralph P. Braun · Katrin Kerl · Oriol Yélamos|
|Responsible author||Ralph Braun → send e-mail|
|Status update||May 27, 2019|
|Status by||Ralph P. Braun|
In this chapter we describe blue white structures network and its histopathological correlation
It has the following subchapters:
|White scar-like depigmentation||Ralph P. Braun, Oriol Yélamos|
|Granularity / Peppering||Ralph P. Braun, Oriol Yélamos|
|Blue whitish veil||Ralph P. Braun, Katrin Kerl, Oriol Yélamos|
On histopathologyThis glossary term has not yet been described. fully evolved regression shows fibrosis and melanosis (infiltrate of melanophages), and sparse lymphocytic infiltrates. The normal undulating DEJ pattern formed by rete ridgesEpidermal extensions that project into the underlying dermis and dermal papillae is attenuated to completely Flattened. Regression structuresThis glossary term has not yet been described. consisting of both scar like depigmentation and peppering (granularityThis glossary term has not yet been described.) should raise suspicion for melanomaThis glossary term has not yet been described.. Regression structures consisting of only peppering can be seen in melanoma, lichen planus like keratosisThis glossary term has not yet been described. and neviThis glossary term has not yet been described.. In lichen planus like keratosis the granularity tends to be coarse and diffusely distributed. In melanocyticThis glossary term has not yet been described. lesions the granularity tends to be finer and focally distributed.
These areas should not be chosen for sectioning when grossing a suspected melanoma as they may reveal non-diagnostic features or underestimate the Breslow thickness.