Long Term Monitoring

From dermoscopedia

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 Authored by: Florentia Dimitriou     ·  Harald Kittler

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Author(s) Florentia Dimitriou · Harald Kittler
Owner Harald Kittler→ send e-mail
Status released
Status update August 20, 2017
Status by Ralph P. Braun

Long Term Monitoring

  • Is mainly used for randomly selected lesions with no features to suggest malignancy, typically in patients with multiple neviThis glossary term has not yet been described..
  • Long-term follow-up changes observed in melanomas are different from those observed in nevi.
  • Melanomas more frequently grow asymmetrically (change in size and shape), whereas nevi more frequently grow symmetrically (size but not in shape).
  • Structural changes and colorColor (American English) or colour (Commonwealth English) is the characteristic of human visual perception described through color categories, with names such as red, yellow, purple, or blue. changes are more frequently observes in melanomas than in nevi.

Classificationis a general process related to categorization, the process in which ideas and objects are recognized, differentiated, and understood. of Changes

Significant change Non-significant change
Asymmetric enlargement Darker or lighter overall appearance
Focal changes in pigmentation or structure Change in number or distribution of brown globulesThis glossary term has not yet been described.
RegressionThis glossary term has not yet been described. features Decrease in number of black dotsDots are small, round structures of less than 0.1 mm in diameter that have a red color when corresponding to blood vessels; however, when due to melanin, their color ranges from black, brown, to blue-gray depending on the depth and concentration of the melanin in the skin (Tyndall effect).
Change in color Disappearance of inflammatory reaction
Disappearance of small foci of pigment network within central portion of the lesion and replacement by diffuse brown pigmentation

ManagementThis glossary term has not yet been described. approach for nevi with peripheral grim of globules

In contrast to melanomas, enlarging melanocyticThis glossary term has not yet been described. nevi typically show symmetrical enlargement without structural changes. The dermoscopic sign of peripheral rim of brown globulesGlobules distributed at the periphery of lesion is highly characteristic for symmetrically enlarging melanocytic nevi in youth. Once these nevi enter senescence, the peripheral globulesThis glossary term has not yet been described. are no longer visible and the nevus will usually manifest a reticular or homogenous patternstructureless any color.

<20 years old 20–50 years old >50 years old
Reassure Follow-up to insure normal growth and behavior (STMM) Digitally monitor until senescent. If not able to digitally monitor then consider biopsy

  1. An Atlas of DermoscopyDermoscopy is a non invasive diagnostic method., Second Edition. Marghoob A. et al. CRC Press; 2012.
  2. Argenziano, G., Kittler, H., Ferrara, G., et al., 2010, Slow-growing melanomaThis glossary term has not yet been described.: a dermoscopyDermoscopy is a non invasive diagnostic method. follow-up study. Br J Dermatol, 162, 267–73.
  3. Argenziano, G., Zalaudek, I. & Ferrara, G., 2007, Fast-growing and slow-growing melanomas. Arch Dermatol, 143, 802–3; author reply 803–4.
  4. Banky, J.P., Kelly, J.W., English, D.R., Yeatman, J.M. & Dowling, J.P., 2005, Incidence of new and changed nevi and melanomas detected using baseline images and dermoscopy in patients at high risk for melanoma. Arch Dermatol, 141, 998–1006.
  5. Dawid, M., Pehamberger, H., Wolff, K., Binder, M. & Kittler, H., 2002, Evaluation of the ability of patients to identify enlarging melanocytic nevi. Arch Dermatol, 138, 984–5. Fuller, S.R., Bowenalso known as squamous cell carcinoma in situ[1] is a neoplastic skin disease. It can be considered as an early stage or intraepidermal form of squamous cell carcinoma. It was named after John T. Bowen, G.M., Tanner, B., Florell, S.R. & Grossman, D., 2007, Digital dermoscopic monitoring of atypical neviNevi that clinically look like melanoma but that histopathologically are not melanomas in patients at risk for melanoma. Dermatol Surg, 33, 1198–206; discussion 1205–6.
  6. Kittler, H. & Binder, M., 2001, Risks and benefits of sequential imaging of melanocytic skin lesions in patients with multiple atypical nevi. Arch Dermatol, 137, 1590–5.
  7. Kittler, H. & Binder, M., 2002, Follow-up of melanocytic skin lesions with digital dermoscopyDermoscopy using digital images. This is used for telemedicine and monitoring.: risks and benefits. Archives of Dermatology, 138, 1379.
  8. Kittler, H., Guitera, P., Riedl, E., et al., 2006, Identification of clinically featureless incipient melanoma using sequential dermoscopy imagingThis glossary term has not yet been described.. Arch Dermatol, 142,
  9. 1113–19.
  10. Kittler, H., Pehamberger, H., Wolff, K. & Binder, M., 2000a, Follow-up of melanocytic skin lesions with digital epiluminescence microscopy: patterns of modifications observed in early melanoma, atypical nevi, and common nevi. J Am Acad Dermatol, 43, 467–76.
  11. Kittler, H., Seltenheim, M., Dawid, M., et al., 2000b, Frequency and characteristics of enlarging common melanocytic nevi. Arch Dermatol, 136, 316–20.
  12. Schiffner, R., Schiffner-Rohe, J., Landthaler, M. & Stolz, W., 2003, Long-term dermoscopic follow-up of melanocytic naevi: clinical outcome and patient compli- ance. Br J Dermatol, 149, 79–86.
  13. Terushkin, V., Dusza, S.W., Scope, A., et al., 2012, Changes observed in slow-growing melanomas during long-term dermoscopic monitoring. Br J Dermatol, 166, 1213–20.
  14. Zalaudek, I., Karin, S., Marghoob, A., et al., 2011, Frequency of dermoscopic nevus subtypes by ageprocess of becoming older and body sitedescribes the area of the body: a Cross-sectional Study. Arch Dermatol, 147, 663–70.