Long Term Monitoring

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 Authored by: Florentia Dimitriou     ·  Harald Kittler

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Author(s) Florentia Dimitriou · Harald Kittler
Owner Harald Kittler→ send e-mail
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Status update August 20, 2017
Status by Ralph P. Braun
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Long Term Monitoring

  • Is mainly used for randomly selected lesions with no features to suggest malignancy, typically in patients with multiple neviThis glossary term has not yet been described..
  • Long-term follow-up changes observed in melanomas are different from those observed in nevi.
  • Melanomas more frequently grow asymmetrically (change in size and shape), whereas nevi more frequently grow symmetrically (size but not in shape).
  • Structural changes and colorColor (American English) or colour (Commonwealth English) is the characteristic of human visual perception described through color categories, with names such as red, yellow, purple, or blue. changes are more frequently observes in melanomas than in nevi.

ClassificationThis glossary term has not yet been described. of Changes

Significant change Non-significant change
Asymmetric enlargement Darker or lighter overall appearance
Focal changes in pigmentation or structure Change in number or distribution of brown globulesThis glossary term has not yet been described.
RegressionThis glossary term has not yet been described. features Decrease in number of black dotsThis glossary term has not yet been described.
Change in color Disappearance of inflammatory reaction
Disappearance of small foci of pigment network within central portion of the lesion and replacement by diffuse brown pigmentation

ManagementThis glossary term has not yet been described. approach for nevi with peripheral grim of globules

In contrast to melanomas, enlarging melanocyticThis glossary term has not yet been described. nevi typically show symmetrical enlargement without structural changes. The dermoscopic sign of peripheral rim of brown globulesGlobules distributed at the periphery of lesion is highly characteristic for symmetrically enlarging melanocytic nevi in youth. Once these nevi enter senescence, the peripheral globulesThis glossary term has not yet been described. are no longer visible and the nevus will usually manifest a reticular or homogenous pattern.


<20 years old 20–50 years old >50 years old
Reassure Follow-up to insure normal growth and behavior (STMM) Digitally monitor until senescent. If not able to digitally monitor then consider biopsy


References
  1. An Atlas of DermoscopyDermoscopy is a non invasive diagnostic method., Second Edition. Marghoob A. et al. CRC Press; 2012.
  2. Argenziano, G., Kittler, H., Ferrara, G., et al., 2010, Slow-growing melanomaThis glossary term has not yet been described.: a dermoscopyDermoscopy is a non invasive diagnostic method. follow-up study. Br J Dermatol, 162, 267–73.
  3. Argenziano, G., Zalaudek, I. & Ferrara, G., 2007, Fast-growing and slow-growing melanomas. Arch Dermatol, 143, 802–3; author reply 803–4.
  4. Banky, J.P., Kelly, J.W., English, D.R., Yeatman, J.M. & Dowling, J.P., 2005, Incidence of new and changed nevi and melanomas detected using baseline images and dermoscopy in patients at high risk for melanoma. Arch Dermatol, 141, 998–1006.
  5. Dawid, M., Pehamberger, H., Wolff, K., Binder, M. & Kittler, H., 2002, Evaluation of the ability of patients to identify enlarging melanocytic nevi. Arch Dermatol, 138, 984–5. Fuller, S.R., BowenThis glossary term has not yet been described., G.M., Tanner, B., Florell, S.R. & Grossman, D., 2007, Digital dermoscopic monitoring of atypical neviThis glossary term has not yet been described. in patients at risk for melanoma. Dermatol Surg, 33, 1198–206; discussion 1205–6.
  6. Kittler, H. & Binder, M., 2001, Risks and benefits of sequential imaging of melanocytic skin lesions in patients with multiple atypical nevi. Arch Dermatol, 137, 1590–5.
  7. Kittler, H. & Binder, M., 2002, Follow-up of melanocytic skin lesions with digital dermoscopyThis glossary term has not yet been described.: risks and benefits. Archives of Dermatology, 138, 1379.
  8. Kittler, H., Guitera, P., Riedl, E., et al., 2006, Identification of clinically featureless incipient melanoma using sequential dermoscopy imagingThis glossary term has not yet been described.. Arch Dermatol, 142,
  9. 1113–19.
  10. Kittler, H., Pehamberger, H., Wolff, K. & Binder, M., 2000a, Follow-up of melanocytic skin lesions with digital epiluminescence microscopy: patterns of modifications observed in early melanoma, atypical nevi, and common nevi. J Am Acad Dermatol, 43, 467–76.
  11. Kittler, H., Seltenheim, M., Dawid, M., et al., 2000b, Frequency and characteristics of enlarging common melanocytic nevi. Arch Dermatol, 136, 316–20.
  12. Schiffner, R., Schiffner-Rohe, J., Landthaler, M. & Stolz, W., 2003, Long-term dermoscopic follow-up of melanocytic naevi: clinical outcome and patient compli- ance. Br J Dermatol, 149, 79–86.
  13. Terushkin, V., Dusza, S.W., Scope, A., et al., 2012, Changes observed in slow-growing melanomas during long-term dermoscopic monitoring. Br J Dermatol, 166, 1213–20.
  14. Zalaudek, I., Karin, S., Marghoob, A., et al., 2011, Frequency of dermoscopic nevus subtypes by ageprocess of becoming older and body siteThis glossary term has not yet been described.: a Cross-sectional Study. Arch Dermatol, 147, 663–70.