Multiple Blue-Gray Non-aggregated Dots and Globules

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Main PageHistopathological correlationMultiple Blue-Gray Non-aggregated Dots and Globules
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 Editor: Ralph P. Braun

 Author(s): Ralph P. Braun     ·  Katrin Kerl
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Description In this chapter we describe multiple blue gray dots and globules[[Multiple Blue-Gray Non-aggregated Dots and Globules]] and its histopathological correlation
Author(s) Ralph P. Braun · Katrin Kerl
Responsible author Ralph Braun→ send e-mail
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Status update May 27, 2017
Status by Ralph P. Braun


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Multiple blue-gray dots and globules are round, discrete, and well circumscribed structuresThis glossary term has not yet been described. that, in the absence of a pigment networkGrid-like pattern consisting of interconnecting pigmented lines surrounding hypopigmented holes., are highly suggestive of a basal cell carcinomais the most common skin cancer, and one of the most common cancers in the United States.[1] While BCC has a very low metastatic risk, this tumor can cause significant disfigurement by invading surrounding tissues. These dots and globules usually do not form aggregates as seen in melanocyticThis glossary term has not yet been described. lesions. They correlate with dermal aggregates of pigmented basal cell carcinomaThis glossary term has not yet been described. and are similar to ovoid nests, but smaller [1].

Blue gray ovoid nests and globules BCC schematic.jpg
Blue-gray globules &dots.jpg


ReferencesThis is material contained in a footnote or bibliography holding further information.
  1. Lallas et al.: DermoscopyThe examination of [skin lesions] with a 'dermatoscope'. This traditionally consists of a magnifier (typically x10), a non-polarised light source, a transparent plate and a liquid medium between the instrument and the skin, and allows inspection of skin lesions unobstructed by skin surface reflections. Modern dermatoscopes dispense with the use of liquid medium and instead use polarised light to cancel out skin surface reflections. in the diagnosisis the identification of the nature and cause of a certain phenomenon. Diagnosis is used in many different disciplines with variations in the use of logic, analytics, and experience to determine "cause and effect". In systems engineering and computer science, it is typically used to determine the causes of symptoms, mitigations, and solutions and managementThis glossary term has not yet been described. of basal cell carcinoma. Future Oncol 2015;11:2975-84. PMID: 26450622. DOI.