Spoke wheel like structures
|Description||In this chapter we describe spoke wheel like structuresThis glossary term has not yet been described. and its histopathological correlation|
|Author(s)||Ralph P. Braun · Katrin Kerl|
|Responsible author||Ralph Braun → send e-mail|
|Status update||May 27, 2017|
|Status by||Ralph P. Braun|
Spoke-wheel-like structuresThis glossary term has not yet been described. are well-circumscribed brown to gray-blue– brown radial projections that radiate out from a dark brown central hub. Sometimes the radial projections are not visible and instead one sees a concentric globuleThis glossary term has not yet been described. consisting of a round structure with a central darker hub, which is surrounded by a brown halo of pigment. In the absence of a pigment networkGrid-like pattern consisting of interconnecting pigmented lines surrounding hypopigmented holes., spoke-wheels are highly suggestive of basal cell carcinomais the most common skin cancer, and one of the most common cancers in the United States. While BCC has a very low metastatic risk, this tumor can cause significant disfigurement by invading surrounding tissues.
Histopathologically, they correspond to the nests of basal cell carcinoma emanating from the undersurface of the epidermis; a common finding in superficialThis glossary term has not yet been described. basal cell carcinoma .
ReferencesThis is material contained in a footnote or bibliography holding further information.
- Lallas et al.: DermoscopyThe examination of [skin lesions] with a 'dermatoscope'. This traditionally consists of a magnifier (typically x10), a non-polarised light source, a transparent plate and a liquid medium between the instrument and the skin, and allows inspection of skin lesions unobstructed by skin surface reflections. Modern dermatoscopes dispense with the use of liquid medium and instead use polarised light to cancel out skin surface reflections. in the diagnosisis the identification of the nature and cause of a certain phenomenon. Diagnosis is used in many different disciplines with variations in the use of logic, analytics, and experience to determine "cause and effect". In systems engineering and computer science, it is typically used to determine the causes of symptoms, mitigations, and solutions and managementThis glossary term has not yet been described. of basal cell carcinoma. Future Oncol 2015;11:2975-84. PMID: 26450622. DOI.