Dots are small, round structures of less than 0.1 mm in diameter that have a red colorColor (American English) or colour (Commonwealth English) is the characteristic of human visual perception described through color categories, with names such as red, yellow, purple, or blue. when corresponding to blood vesselsThis glossary term has not yet been described.; however, when due to melanin, their color ranges from black, brown, to blue-gray depending on the depth and concentration of the melanin in the skin (Tyndall effect). Black dots are often due to melanin pigment accumulation in the stratum corneum, but can also be due to vertical stacking of pigment within the epidermis or due to heavy aggregates of melanin in small clusters of melanocytes or keratinocytes located in the upper layers of the epidermis (just below the stratum corneum). Black dots that are in the stratum corneum are usually found overlying the gridlines of the network and they can easily be tape stripped off the skinThis glossary term has not yet been described.. Brown dots are often associated with focal melanin accumulations at the DEJ or spinous layer and they usually correspond histologically to small junctional melanocyticThis glossary term has not yet been described. nests. The dotsThis glossary term has not yet been described., resulting from nevus nests located at the tips of rete ridges, tend to be situated overlying the network linesstreaks. Less frequently, brown dots correspond to melanocytic nests located in the skin below the stratum corneum or even within the stratum corneum. The nests present within the stratum corneum are probably in the process of being extruded from the skin via transelimination. Brown dots corresponding to small melanocytic nests situated in the papillary dermis appear as dots situated within the holes of the network. These so-called target network with dots/globules or halo dots/globules are a common finding in congenital melanocytic neviThis glossary term has not yet been described.. Although on rare occasions brown dots can be tape stripped off the skin, most brown dots cannot be removed via tapestripping. Black or brown dots may appear after acute ultraviolet exposure; however, these dots tend to disappear over time. It is interesting to note that many non–ultraviolet-induced dots that are successfully tape stripped off the skin reappear with time. Gray-blue dots (also called granules or peppering) are due to fi ne melanin particles within melanophages or as extracellular “dust” in the superficialThis glossary term has not yet been described. dermis; a feature associated with regressionThis glossary term has not yet been described..
Regular dotsDots clustered at the center of the lesion, or located on the network lines (also called target network)Dots clustered at the center of the lesion, or located on the network lines (also called target network)
Irregular dots tend to be heterogenous in size shabe and color and are frequently found at the periphery of a given lesion or scattered throughout the lesion.