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Dermoscopy evaluates the lesion in all its extensions on a horizontal plane. This can allow the selection of the best area to biopsy in large lesions, as well as giving information to the pathologist of the most representative area to section. Improvement in sampling can occur either using dermoscopy in the clinical setting or by using dermoscopy directly in the excised specimen in the laboratory (ex vivo dermoscopy). Ex vivo dermoscopy (EVD) is a valuable tool since most dermoscopic features are visible even after formalin fixation.
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Subungual Squamous cell carcinoma
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