Structureless areas (full text)
|Description||In this chapter we describe the dermoscopyThe examination of [skin lesions] with a 'dermatoscope'. This traditionally consists of a magnifier (typically x10), a non-polarised light source, a transparent plate and a liquid medium between the instrument and the skin, and allows inspection of skin lesions unobstructed by skin surface reflections. Modern dermatoscopes dispense with the use of liquid medium and instead use polarised light to cancel out skin surface reflections. term structureless areas and their histopathological correlation including regular blotches, irregular blotches|
|Author(s)||Ralph P. Braun · Katrin Kerl|
|Responsible author||Ralph Braun → send e-mail|
|Status update||July 27, 2017|
|Status by||Ralph P. Braun|
Areas within a lesion that are devoid of any networkThis glossary term has not yet been described. or other structuresThis glossary term has not yet been described., such as globules or regression structuresThis glossary term has not yet been described., are called “structureless areas.” Structureless areas are defined as areas with a size that is at least 10% of the lesion’s surface area and are devoid of any discernible structures, such as globulesThis glossary term has not yet been described., network, or regression structures (i.e., scars, pepperingGray dots, granularityThis glossary term has not yet been described., or blue-white veil over fl at areas).
neviThis glossary term has not yet been described.. However, focal tan to light brown structureless areas at the periphery of a melanocyticThis glossary term has not yet been described. lesion is commonly associated with melanomaThis glossary term has not yet been described.. Peripherally located structureless areas in melanoma tend to have a light brown to fawn color and tend to end abruptly at the edge of a lesion. Histologically, these areas are characterized by flattening of the DEJ (loss of the undulating pattern of rete ridgesEpidermal extensions that project into the underlying dermis and dermal papillae) and scattering of atypical melanocytes in suprabasal epidermal layers (i.e., pagetoid cells).
Structureless areas, hyperpigmented (Blotches)A blotchDark structureless areas is defined as an area with a size that is at least 10% of the lesion’s surface area and is heavily pigmentedThis glossary term has not yet been described.. In a blotch the melanin pigment is often present throughout the skinThis glossary term has not yet been described., including the stratum corneum, epidermis, and the dermis. The dark pigment in a blotch visually obscures the ability to discern any underlying structures. Blotches can be regular or irregular.
Regular hyperpigmented structureless areaThis glossary term has not yet been described. (BlotchDark structureless areas)
Regular blotches are defined as those that display symmetry, regular borders,homogenous dark hue, and are located within the center of the lesion. A pigment network often surrounds a regular blotchOne blotch within center of lesion and surrounded by network. Regular blotches are associated with nevi.
Regular blotches can be seen in “activated” nevi. This structure is due to heavy concentrations of melanin in the stratum corneum. Because the pigment is present in the stratum corneum, it can easily be stripped off using a tape-stripping procedure, thereby revealing underlying structures.